N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide
TL;DR: N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide (CAS 194423-06-8) is a chemical compound with molecular formula C18H13BrN4O and molecular weight 380.02728 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[4-(3-bromoanilino)quinazolin-6-yl]but-2-ynamide
Also Known As: WAY-EKI-785, N-(4-((3-bromophenyl)amino)quinazolin-6-yl)but-2-ynamide, 4-anilinoquinazoline deriv. 1, EKI 785, CL-387,785
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H13BrN4O |
| Molecular Weight | 380.02728 g/mol |
| XLogP | 4.3 |
| Topological Polar Surface Area (TPSA) | 66.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 380.02728 Da |
| Heavy Atoms | 24 |
| Complexity | 514.0 |
| SMILES | CC#CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br |
| InChIKey | BTYYWOYVBXILOJ-UHFFFAOYSA-N |
Product Description
Applications: N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide (CAS 194423-06-8) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide (CAS 194423-06-8) has the molecular formula C18H13BrN4O and a molecular weight of 380.03 g/mol. It is also known as cl-387785 and EKI-785.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide
Property Insights of N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide
The XLogP value of 4.3 indicates that N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.9 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide. Following Lipinski's Rule of Five, N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide?
The CAS number of N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide is 194423-06-8.
What is the molecular formula of N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide?
The molecular formula of N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide is C18H13BrN4O.
What is the molecular weight of N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide?
The molecular weight of N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide is 380.02728 g/mol.
What are the applications of N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide?
N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem...
Where can I buy N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide?
You can request a quote for N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide?
Yes, CoreyChem provides custom synthesis services for N-(4-((3-bromophenyl)amino)-6-quinazolinyl)-2-butynamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.