Loxapine
TL;DR: Loxapine (CAS 1977-10-2) is a chemical compound with molecular formula C18H18ClN3O and molecular weight 327.11383 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
Also Known As: loxapine, Cloxazepine, Oxilapine, Loxapin, Loxitane
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H18ClN3O |
| Molecular Weight | 327.11383 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 28.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 327.11383 Da |
| Heavy Atoms | 23 |
| Complexity | 450.0 |
| Melting Point | 109-111 °C |
| Solubility | 1.03e-01 g/L |
| SMILES | CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl |
| InChIKey | XJGVXQDUIWGIRW-UHFFFAOYSA-N |
Chemical Property Profile of Loxapine
Property Insights of Loxapine
The XLogP value of 3.1 indicates that Loxapine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.1 Ų, Loxapine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Loxapine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Loxapine?
The CAS number of Loxapine is 1977-10-2.
What is the molecular formula of Loxapine?
The molecular formula of Loxapine is C18H18ClN3O.
What is the molecular weight of Loxapine?
The molecular weight of Loxapine is 327.11383 g/mol.
Where can I buy Loxapine?
You can request a quote for Loxapine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Loxapine?
Yes, CoreyChem provides custom synthesis services for Loxapine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.