Trazodone
TL;DR: Trazodone (CAS 19794-93-5) is a chemical compound with molecular formula C19H22ClN5O and molecular weight 371.15128 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Also Known As: trazodone, Trazodon, Beneficat, Trazodona, Trazalon
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C19H22ClN5O |
| Molecular Weight | 371.15128 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 42.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 371.15128 Da |
| Heavy Atoms | 26 |
| Complexity | 611.0 |
| Melting Point | 231-234 |
| Boiling Point | 528.5 |
| Solubility | 2.90e-01 g/L |
| SMILES | C1CN(CCN1CCCN2C(=O)N3C=CC=CC3=N2)C4=CC(=CC=C4)Cl |
| InChIKey | PHLBKPHSAVXXEF-UHFFFAOYSA-N |
Product Description
Applications: Trazodone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Trazodone (CAS 19794-93-5) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Trazodone (CAS 19794-93-5) has the molecular formula C19H22ClN5O and a molecular weight of 371.15 g/mol. Reported properties include a solubility: 2.90e-01 g/L. It is also known as trazodone and Trazodon.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Trazodone
Property Insights of Trazodone
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trazodone. With a topological polar surface area (TPSA) of 42.4 Ų, Trazodone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Trazodone has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Trazodone?
The CAS number of Trazodone is 19794-93-5.
What is the molecular formula of Trazodone?
The molecular formula of Trazodone is C19H22ClN5O.
What is the molecular weight of Trazodone?
The molecular weight of Trazodone is 371.15128 g/mol.
What are the applications of Trazodone?
Trazodone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Trazodone (CAS 19794-93-5) with custom...
Where can I buy Trazodone?
You can request a quote for Trazodone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Trazodone?
Yes, CoreyChem provides custom synthesis services for Trazodone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.