Parecoxib
TL;DR: Parecoxib (CAS 198470-84-7) is a chemical compound with molecular formula C19H18N2O4S and molecular weight 370.09872 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonylpropanamide
Also Known As: Parecoxib, Xapit, Dynastat, Rayzon, parecoxibum
Application Areas
Top 5 of 11 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C19H18N2O4S |
| Molecular Weight | 370.09872 g/mol |
| XLogP | 3.3 |
| Topological Polar Surface Area (TPSA) | 97.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 370.09872 Da |
| Heavy Atoms | 26 |
| Complexity | 575.0 |
| SMILES | CCC(=O)NS(=O)(=O)C1=CC=C(C=C1)C2=C(ON=C2C3=CC=CC=C3)C |
| InChIKey | TZRHLKRLEZJVIJ-UHFFFAOYSA-N |
Chemical Property Profile of Parecoxib
Property Insights of Parecoxib
The XLogP value of 3.3 indicates that Parecoxib is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 97.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Parecoxib. Following Lipinski's Rule of Five, Parecoxib has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Parecoxib?
The CAS number of Parecoxib is 198470-84-7.
What is the molecular formula of Parecoxib?
The molecular formula of Parecoxib is C19H18N2O4S.
What is the molecular weight of Parecoxib?
The molecular weight of Parecoxib is 370.09872 g/mol.
Where can I buy Parecoxib?
You can request a quote for Parecoxib directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Parecoxib?
Yes, CoreyChem provides custom synthesis services for Parecoxib and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.