PMPA prodrug

[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(2-methylpropoxycarbonyloxymethoxy)phosphoryl]oxymethyl 2-methylpropyl carbonate

Also Known As: PMPA prodrug|Bis(IsobutylOC)PMPA|Tenofovir prodrug|2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-((2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)-, bis(2-methylpropyl) ester, 5-oxide, (R)-|[[(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-(isobutoxycarbonyloxymethoxy)phosphoryl]oxymethyl isobutyl carbonate|[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(2-methylpropoxycarbonyloxymethoxy)phosphoryl]oxymethyl 2-methylpropyl carbonate|2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, bis(2-methylpropyl) ester, 5-oxide, (R)-|Bis({[(2-methylpropoxy)carbonyl]oxy}methyl) ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate

Molecular Formula	C21H34N5O10P
Molecular Weight	547.20435 g/mol
LogP	3.5308
Topological Polar Surface Area	185.44 Ų
Hydrogen Bond Donors	1
Hydrogen Bond Acceptors	14
Rotatable Bonds	15
Exact Mass	547.20435
Monoisotopic Mass	547.20435
Heavy Atoms	37
Complexity	1029.515

Chemical Identifiers

CAS Number	201340-99-0
SMILES	C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(OCOC(=O)OCC(C)C)OCOC(=O)OCC(C)C