Clofazimine
TL;DR: Clofazimine (CAS 2030-63-9) is a chemical compound with molecular formula C27H22Cl2N4 and molecular weight 472.12216 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N,5-bis(4-chlorophenyl)-3-propan-2-yliminophenazin-2-amine
Also Known As: clofazimine, Lamprene, Chlofazimine, Lampren, Clofazimina
Application Areas
Top 5 of 19 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C27H22Cl2N4 |
| Molecular Weight | 472.12216 g/mol |
| XLogP | 7.1 |
| Topological Polar Surface Area (TPSA) | 40.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 472.12216 Da |
| Heavy Atoms | 33 |
| Complexity | 829.0 |
| Melting Point | 210-212 °C |
| Solubility | 0.225 |
| SMILES | CC(C)N=C1C=C2C(=NC3=CC=CC=C3N2C4=CC=C(C=C4)Cl)C=C1NC5=CC=C(C=C5)Cl |
| InChIKey | WDQPAMHFFCXSNU-UHFFFAOYSA-N |
Product Description
Applications: Clofazimine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Clofazimine (CAS 2030-63-9) has the molecular formula C27H22Cl2N4 and a molecular weight of 472.12 g/mol. Reported properties include a solubility: 0.225. Synonyms include clofazimine and Lamprene.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Clofazimine
Property Insights of Clofazimine
The XLogP value of 7.1 indicates that Clofazimine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.0 Ų, Clofazimine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Clofazimine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Clofazimine?
The CAS number of Clofazimine is 2030-63-9.
What is the molecular formula of Clofazimine?
The molecular formula of Clofazimine is C27H22Cl2N4.
What is the molecular weight of Clofazimine?
The molecular weight of Clofazimine is 472.12216 g/mol.
What are the applications of Clofazimine?
Clofazimine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Clofazimine?
You can request a quote for Clofazimine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Clofazimine?
Yes, CoreyChem provides custom synthesis services for Clofazimine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.