VEGFR2 Kinase Inhibitor II
TL;DR: VEGFR2 Kinase Inhibitor II (CAS 204003-89-4) is a chemical compound with molecular formula C17H15BrN2O and molecular weight 342.03677 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indol-2-one
Also Known As: VEGFR2 Kinase Inhibitor II, VEGF Receptor 2 Kinase Inhibitor II, 5-Bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-2H-indol-2-one, 5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indol-2-one, (3Z)-5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indol-2-one
Application Areas
Top 5 of 1 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H15BrN2O |
| Molecular Weight | 342.03677 g/mol |
| XLogP | 3.6 |
| Topological Polar Surface Area (TPSA) | 44.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 342.03677 Da |
| Heavy Atoms | 21 |
| Complexity | 464.0 |
| SMILES | C1CCC2=C(C1)C=C(N2)C=C3C4=C(C=CC(=C4)Br)NC3=O |
| InChIKey | RFHPWPWVGFSLOP-UHFFFAOYSA-N |
Chemical Property Profile of VEGFR2 Kinase Inhibitor II
Property Insights of VEGFR2 Kinase Inhibitor II
The XLogP value of 3.6 indicates that VEGFR2 Kinase Inhibitor II is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.9 Ų, VEGFR2 Kinase Inhibitor II exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, VEGFR2 Kinase Inhibitor II has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of VEGFR2 Kinase Inhibitor II?
The CAS number of VEGFR2 Kinase Inhibitor II is 204003-89-4.
What is the molecular formula of VEGFR2 Kinase Inhibitor II?
The molecular formula of VEGFR2 Kinase Inhibitor II is C17H15BrN2O.
What is the molecular weight of VEGFR2 Kinase Inhibitor II?
The molecular weight of VEGFR2 Kinase Inhibitor II is 342.03677 g/mol.
Where can I buy VEGFR2 Kinase Inhibitor II?
You can request a quote for VEGFR2 Kinase Inhibitor II directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for VEGFR2 Kinase Inhibitor II?
Yes, CoreyChem provides custom synthesis services for VEGFR2 Kinase Inhibitor II and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.