Amifostine
TL;DR: Amifostine (CAS 20537-88-6) is a chemical compound with molecular formula C5H15N2O3PS and molecular weight 214.05411 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(3-aminopropylamino)ethylsulfanylphosphonic acid
Also Known As: amifostine, Ethiofos, Gammaphos, Ethyol, Sapep
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C5H15N2O3PS |
| Molecular Weight | 214.05411 g/mol |
| XLogP | -4.5 |
| Topological Polar Surface Area (TPSA) | 121.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 214.05411 Da |
| Heavy Atoms | 12 |
| Complexity | 152.0 |
| Solubility | 1000 |
| SMILES | C(CN)CNCCSP(=O)(O)O |
| InChIKey | JKOQGQFVAUAYPM-UHFFFAOYSA-N |
Chemical Property Profile of Amifostine
Property Insights of Amifostine
The XLogP value of -4.5 indicates that Amifostine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 121.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Amifostine. Following Lipinski's Rule of Five, Amifostine has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Amifostine?
The CAS number of Amifostine is 20537-88-6.
What is the molecular formula of Amifostine?
The molecular formula of Amifostine is C5H15N2O3PS.
What is the molecular weight of Amifostine?
The molecular weight of Amifostine is 214.05411 g/mol.
Where can I buy Amifostine?
You can request a quote for Amifostine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Amifostine?
Yes, CoreyChem provides custom synthesis services for Amifostine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.