Osmium Tetroxide
TL;DR: Osmium Tetroxide (CAS 20816-12-0) is a chemical compound with molecular formula O4Os and molecular weight 255.94115 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
tetraoxoosmium
Also Known As: OSMIUM TETROXIDE, Osmium tetraoxide, tetraoxoosmium, Osmic acid, Perosmic oxide
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | O4Os |
| Molecular Weight | 255.94115 g/mol |
| XLogP | -0.48 |
| Topological Polar Surface Area (TPSA) | 68.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 0 |
| Exact Mass | 255.94115 Da |
| Heavy Atoms | 5 |
| Complexity | 138.0 |
| Melting Point | 105 °F (NIOSH, 2024) |
| Boiling Point | 266 °F at 760 mmHg (NIOSH, 2024) |
| Density | 5.1 (NIOSH, 2024) - Denser than water; will sink |
| Vapor Pressure | 7 mmHg (NIOSH, 2024) |
| Solubility | 6 % at 77 °F (NIOSH, 2024) |
| SMILES | O=[Os](=O)(=O)=O |
| InChIKey | VUVGYHUDAICLFK-UHFFFAOYSA-N |
Product Description
Applications: Osmium Tetroxide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as an oxidizing agent in synthetic sequences. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Osmium Tetroxide is a pharmaceutical intermediate identified by CAS number 20816-12-0 and the molecular formula O4Os and a molecular weight of 255.94 g/mol. Physically, the compound has a density of 5.1 (NIOSH, 2024) - Denser than water; will sink g/cm³, a solubility: 6 % at 77 °F (NIOSH, 2024). Synonyms include OSMIUM TETROXIDE and Osmium tetraoxide.
Custom synthesis (mg to ton scale), HPLC/NMR/MS analytical support, and complete COA/MSDS documentation are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Safety Information
H302 + H332, H310, H315, H318
Chemical Property Profile of Osmium Tetroxide
Property Insights of Osmium Tetroxide
The XLogP value of -0.48 indicates that Osmium Tetroxide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 68.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Osmium Tetroxide. Following Lipinski's Rule of Five, Osmium Tetroxide has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Osmium Tetroxide?
The CAS number of Osmium Tetroxide is 20816-12-0.
What is the molecular formula of Osmium Tetroxide?
The molecular formula of Osmium Tetroxide is O4Os.
What is the molecular weight of Osmium Tetroxide?
The molecular weight of Osmium Tetroxide is 255.94115 g/mol.
What are the applications of Osmium Tetroxide?
Osmium Tetroxide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as an oxidizing agent in synthetic sequences. Available from CoreyChem as both catalog item and...
Where can I buy Osmium Tetroxide?
You can request a quote for Osmium Tetroxide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Osmium Tetroxide?
Yes, CoreyChem provides custom synthesis services for Osmium Tetroxide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.