dapt
TL;DR: dapt (CAS 208255-80-5) is a chemical compound with molecular formula C23H26F2N2O4 and molecular weight 432.18607 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
tert-butyl 2-[2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoylamino]-2-phenylacetate
Also Known As: dapt, GSI-IX, DAPT (GSI-IX), A-Secretase Inhibitor Dapt, gamma-Secretase Inhibitor IX
Technical Specifications
| Molecular Formula | C23H26F2N2O4 |
| Molecular Weight | 432.18607 g/mol |
| XLogP | 3.7 |
| Topological Polar Surface Area (TPSA) | 84.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 9 |
| Exact Mass | 432.18607 Da |
| Heavy Atoms | 31 |
| Complexity | 622.0 |
| SMILES | CC(C(=O)NC(C1=CC=CC=C1)C(=O)OC(C)(C)C)NC(=O)CC2=CC(=CC(=C2)F)F |
| InChIKey | DWJXYEABWRJFSP-UHFFFAOYSA-N |
Product Description
Applications: dapt is used in organic synthesis and process chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
dapt is a fine chemical identified by CAS number 208255-80-5 and the molecular formula C23H26F2N2O4 and a molecular weight of 432.19 g/mol. Synonyms include dapt and GSI-IX.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of dapt
Property Insights of dapt
The XLogP value of 3.7 indicates that dapt is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 84.5 Ų falls within the moderate polarity range, balancing permeability and solubility for dapt. Following Lipinski's Rule of Five, dapt has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of dapt?
The CAS number of dapt is 208255-80-5.
What is the molecular formula of dapt?
The molecular formula of dapt is C23H26F2N2O4.
What is the molecular weight of dapt?
The molecular weight of dapt is 432.18607 g/mol.
What are the applications of dapt?
dapt is used in organic synthesis and process chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Where can I buy dapt?
You can request a quote for dapt directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for dapt?
Yes, CoreyChem provides custom synthesis services for dapt and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.