Whi-P154
TL;DR: Whi-P154 (CAS 211555-04-3) is a chemical compound with molecular formula C16H14BrN3O3 and molecular weight 375.02185 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-bromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
Also Known As: WHI-P154, jak3 inhibitor ii, WHI-P 154, JAK inhibitors, MASTPROM
Application Areas
Top 5 of 8 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H14BrN3O3 |
| Molecular Weight | 375.02185 g/mol |
| XLogP | 3.7 |
| Topological Polar Surface Area (TPSA) | 76.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 375.02185 Da |
| Heavy Atoms | 23 |
| Complexity | 390.0 |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)Br)OC |
| InChIKey | CBIAKDAYHRWZCU-UHFFFAOYSA-N |
Chemical Property Profile of Whi-P154
Property Insights of Whi-P154
The XLogP value of 3.7 indicates that Whi-P154 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Whi-P154. Following Lipinski's Rule of Five, Whi-P154 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Whi-P154?
The CAS number of Whi-P154 is 211555-04-3.
What is the molecular formula of Whi-P154?
The molecular formula of Whi-P154 is C16H14BrN3O3.
What is the molecular weight of Whi-P154?
The molecular weight of Whi-P154 is 375.02185 g/mol.
Where can I buy Whi-P154?
You can request a quote for Whi-P154 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Whi-P154?
Yes, CoreyChem provides custom synthesis services for Whi-P154 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.