Flazalone
TL;DR: Flazalone (CAS 21221-18-1) is a chemical compound with molecular formula C19H19F2NO2 and molecular weight 331.1384 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(4-fluorophenyl)-[4-(4-fluorophenyl)-4-hydroxy-1-methylpiperidin-3-yl]methanone
Also Known As: Flazalone, Flazalona, Flazolone, Flumefenine (base), Flazalone (USAN)
Application Areas
Top 5 of 7 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C19H19F2NO2 |
| Molecular Weight | 331.1384 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 40.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 331.1384 Da |
| Heavy Atoms | 24 |
| Complexity | 445.0 |
| SMILES | CN1CCC(C(C1)C(=O)C2=CC=C(C=C2)F)(C3=CC=C(C=C3)F)O |
| InChIKey | PPQZABOURJVKNI-UHFFFAOYSA-N |
Chemical Property Profile of Flazalone
Property Insights of Flazalone
The XLogP value of 3.2 indicates that Flazalone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.5 Ų, Flazalone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Flazalone has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Flazalone?
The CAS number of Flazalone is 21221-18-1.
What is the molecular formula of Flazalone?
The molecular formula of Flazalone is C19H19F2NO2.
What is the molecular weight of Flazalone?
The molecular weight of Flazalone is 331.1384 g/mol.
Where can I buy Flazalone?
You can request a quote for Flazalone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Flazalone?
Yes, CoreyChem provides custom synthesis services for Flazalone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.