5,6-Dihydro-5-(trifluoromethyl)uracil
TL;DR: 5,6-Dihydro-5-(trifluoromethyl)uracil (CAS 2145-56-4) is a chemical compound with molecular formula C5H5F3N2O2 and molecular weight 182.03032 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-(trifluoromethyl)-1,3-diazinane-2,4-dione
Also Known As: 5-(Trifluoromethyl)dihydropyrimidine-2,4(1H,3H)-dione, Trifluorothymine, 5,6-Dihydro-5-(trifluoromethyl)uracil, 5-(Trifluoromethyl)uracil, 5-Fluoro-4-Chromanone
Application Areas
Top 5 of 4 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C5H5F3N2O2 |
| Molecular Weight | 182.03032 g/mol |
| XLogP | 0.0 |
| Topological Polar Surface Area (TPSA) | 58.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 0 |
| Exact Mass | 182.03032 Da |
| Heavy Atoms | 12 |
| Complexity | 225.0 |
| SMILES | C1C(C(=O)NC(=O)N1)C(F)(F)F |
| InChIKey | ACYJXCFDMOGNSM-UHFFFAOYSA-N |
Product Description
Applications: 5,6-Dihydro-5-(trifluoromethyl)uracil is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as complex organic molecule assembly across discovery and process chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 5,6-Dihydro-5-(trifluoromethyl)uracil (CAS 2145-56-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
5,6-Dihydro-5-(trifluoromethyl)uracil is a heterocyclic building block identified by CAS number 2145-56-4 and the molecular formula C5H5F3N2O2 and a molecular weight of 182.03 g/mol. It is also known as 5-(Trifluoromethyl)dihydropyrimidine-2,4(1H,3H)-dione and Trifluorothymine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 5,6-Dihydro-5-(trifluoromethyl)uracil
Property Insights of 5,6-Dihydro-5-(trifluoromethyl)uracil
The XLogP value of 0.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5,6-Dihydro-5-(trifluoromethyl)uracil. With a topological polar surface area (TPSA) of 58.2 Ų, 5,6-Dihydro-5-(trifluoromethyl)uracil exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5,6-Dihydro-5-(trifluoromethyl)uracil has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5,6-Dihydro-5-(trifluoromethyl)uracil?
The CAS number of 5,6-Dihydro-5-(trifluoromethyl)uracil is 2145-56-4.
What is the molecular formula of 5,6-Dihydro-5-(trifluoromethyl)uracil?
The molecular formula of 5,6-Dihydro-5-(trifluoromethyl)uracil is C5H5F3N2O2.
What is the molecular weight of 5,6-Dihydro-5-(trifluoromethyl)uracil?
The molecular weight of 5,6-Dihydro-5-(trifluoromethyl)uracil is 182.03032 g/mol.
What are the applications of 5,6-Dihydro-5-(trifluoromethyl)uracil?
5,6-Dihydro-5-(trifluoromethyl)uracil is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as complex organic molecule assembly across discovery and process chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem...
Where can I buy 5,6-Dihydro-5-(trifluoromethyl)uracil?
You can request a quote for 5,6-Dihydro-5-(trifluoromethyl)uracil directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5,6-Dihydro-5-(trifluoromethyl)uracil?
Yes, CoreyChem provides custom synthesis services for 5,6-Dihydro-5-(trifluoromethyl)uracil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.