p38 MAP Kinase Inhibitor
TL;DR: p38 MAP Kinase Inhibitor (CAS 219138-24-6) is a chemical compound with molecular formula C20H13ClFN3O and molecular weight 365.07312 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(4-chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1H-pyrazol-3-one
Also Known As: p38 MAP Kinase Inhibitor, p38 MAPK Inhibitor, p38 MAPK-IN-4, compound 6 [PMID: 9873604], EX-A11785
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C20H13ClFN3O |
| Molecular Weight | 365.07312 g/mol |
| XLogP | 4.4 |
| Topological Polar Surface Area (TPSA) | 45.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 365.07312 Da |
| Heavy Atoms | 26 |
| Complexity | 547.0 |
| SMILES | C1=CC(=CC=C1C2=C(NN(C2=O)C3=CC=C(C=C3)Cl)C4=CC=NC=C4)F |
| InChIKey | DZFBYHUKZSRPHU-UHFFFAOYSA-N |
Chemical Property Profile of p38 MAP Kinase Inhibitor
Property Insights of p38 MAP Kinase Inhibitor
The XLogP value of 4.4 indicates that p38 MAP Kinase Inhibitor is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.2 Ų, p38 MAP Kinase Inhibitor exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, p38 MAP Kinase Inhibitor has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of p38 MAP Kinase Inhibitor?
The CAS number of p38 MAP Kinase Inhibitor is 219138-24-6.
What is the molecular formula of p38 MAP Kinase Inhibitor?
The molecular formula of p38 MAP Kinase Inhibitor is C20H13ClFN3O.
What is the molecular weight of p38 MAP Kinase Inhibitor?
The molecular weight of p38 MAP Kinase Inhibitor is 365.07312 g/mol.
Where can I buy p38 MAP Kinase Inhibitor?
You can request a quote for p38 MAP Kinase Inhibitor directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for p38 MAP Kinase Inhibitor?
Yes, CoreyChem provides custom synthesis services for p38 MAP Kinase Inhibitor and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.