![3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one structure](/static/products/2207/220749-41-7.webp)
3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one
TL;DR: 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one (CAS 220749-41-7) is a chemical compound with molecular formula C17H11ClN2O and molecular weight 294.056 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one
Also Known As: cdk1 inhibitor, cmpd 8a, CDK1 inhibitor 8a, CDK1-IN-2, 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one
Technical Specifications
| Molecular Formula | C17H11ClN2O |
| Molecular Weight | 294.056 g/mol |
| XLogP | 4.0 |
| Topological Polar Surface Area (TPSA) | 44.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 294.056 Da |
| Heavy Atoms | 21 |
| Complexity | 464.0 |
| SMILES | C1=CC=C2C(=C1)C(=CC3=C(NC4=CC=CC=C43)Cl)C(=O)N2 |
| InChIKey | QJKBRWSJWQVKLY-UHFFFAOYSA-N |
Product Description
Applications: 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one is used in organic synthesis and process chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one is a fine chemical identified by CAS number 220749-41-7 and the molecular formula C17H11ClN2O and a molecular weight of 294.06 g/mol. Synonyms include cdk1 inhibitor and cmpd 8a.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one
Property Insights of 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one
The XLogP value of 4.0 indicates that 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.9 Ų, 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one?
The CAS number of 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one is 220749-41-7.
What is the molecular formula of 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one?
The molecular formula of 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one is C17H11ClN2O.
What is the molecular weight of 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one?
The molecular weight of 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one is 294.056 g/mol.
What are the applications of 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one?
3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one is used in organic synthesis and process chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical...
Where can I buy 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one?
You can request a quote for 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one?
Yes, CoreyChem provides custom synthesis services for 3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.