Ar-67

(19S)-10-[tert-butyl(dimethyl)silyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione

Also Known As: Silatecan|AR-67|DB 67; Silatecan|Silatecan AR-67|AR67|DB-67|AR 67 cpd|AR-67 cpd|DB 67|DB67|GTPL8919|AR 67|7555AD|EX-A14895|NCI60_038363|compound 14 [PMID:11052802]|4-(4-Bromophenyl)-2-methyl-1,3-oxazole|7-t-butyldimethylsilyl-10-hydroxycamptothecin|J1.244.637C|(20S)-7-t-Butyldimethylsilyl-10-hydroxycamptothecin|Z-3160|7-tert-butyldimethylsilyl-10-hydroxy-camptothecin|(S)-11-(tert-Butyldimethylsilyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione|(19S)-10-[tert-butyl(dimethyl)silyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione

Molecular Formula	C26H30N2O5Si
Molecular Weight	478.1924 g/mol
LogP	3.5007
Topological Polar Surface Area	101.65 Ų
Hydrogen Bond Donors	2
Hydrogen Bond Acceptors	6
Rotatable Bonds	2
Exact Mass	478.1924
Monoisotopic Mass	478.1924
Heavy Atoms	34
Complexity	1450.5372

Chemical Identifiers

CAS Number	22091-49-2
SMILES	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C5=C(C=CC(=C5)O)N=C4C3=C2)[Si](C)(C)C(C)(C)C)O