Fosamprenavir
TL;DR: Fosamprenavir (CAS 226700-80-7) is a chemical compound with molecular formula C25H36N3O9PS and molecular weight 585.191 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-1-phenyl-3-phosphonooxybutan-2-yl]carbamate
Also Known As: Fosamprenavir, Telzir, fos-amprenavir, Lexiva, FOS-APV
Application Areas
Top 5 of 9 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C25H36N3O9PS |
| Molecular Weight | 585.191 g/mol |
| XLogP | 1.8 |
| Topological Polar Surface Area (TPSA) | 186.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 14 |
| Exact Mass | 585.191 Da |
| Heavy Atoms | 39 |
| Complexity | 912.0 |
| Solubility | White to cream colored solid. Solubility in water is approximately 0.31 mg/mL at 25 °C /Calcium salt/ |
| SMILES | CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CCOC2)OP(=O)(O)O)S(=O)(=O)C3=CC=C(C=C3)N |
| InChIKey | MLBVMOWEQCZNCC-OEMFJLHTSA-N |
Product Description
Applications: Fosamprenavir is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Fosamprenavir (CAS 226700-80-7) has the molecular formula C25H36N3O9PS and a molecular weight of 585.19 g/mol. Reported properties include a solubility: White to cream colored solid. Solubility in water is approximately 0.31 mg/mL at 25 °C /Calcium salt/. Synonyms include Fosamprenavir and Telzir.
Custom synthesis (mg to ton scale), HPLC/NMR/MS analytical support, and complete COA/MSDS documentation are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Fosamprenavir
Property Insights of Fosamprenavir
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Fosamprenavir. The TPSA of 186.0 Ų indicates high polarity, suggesting Fosamprenavir may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Fosamprenavir has 4 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Fosamprenavir?
The CAS number of Fosamprenavir is 226700-80-7.
What is the molecular formula of Fosamprenavir?
The molecular formula of Fosamprenavir is C25H36N3O9PS.
What is the molecular weight of Fosamprenavir?
The molecular weight of Fosamprenavir is 585.191 g/mol.
What are the applications of Fosamprenavir?
Fosamprenavir is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Fosamprenavir?
You can request a quote for Fosamprenavir directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Fosamprenavir?
Yes, CoreyChem provides custom synthesis services for Fosamprenavir and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.