Miconazole
TL;DR: Miconazole (CAS 22916-47-8) is a chemical compound with molecular formula C18H14Cl4N2O and molecular weight 413.98602 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
Also Known As: miconazole, Monistat, Daktarin IV, Monistat IV, Miconazole nitrate
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H14Cl4N2O |
| Molecular Weight | 413.98602 g/mol |
| XLogP | 5.3 |
| Topological Polar Surface Area (TPSA) | 27.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 6 |
| Exact Mass | 415.98306 Da |
| Heavy Atoms | 25 |
| Complexity | 417.0 |
| Melting Point | 170 |
| Solubility | 7.63e-04 g/L |
| SMILES | C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl |
| InChIKey | BYBLEWFAAKGYCD-UHFFFAOYSA-N |
Product Description
Applications: Miconazole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Miconazole is a pharmaceutical intermediate identified by CAS number 22916-47-8 and the molecular formula C18H14Cl4N2O and a molecular weight of 413.99 g/mol. Physically, the compound has a solubility: 7.63e-04 g/L. Synonyms include miconazole and Monistat.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Miconazole
Property Insights of Miconazole
The XLogP value of 5.3 indicates that Miconazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 27.1 Ų, Miconazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Miconazole has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Miconazole?
The CAS number of Miconazole is 22916-47-8.
What is the molecular formula of Miconazole?
The molecular formula of Miconazole is C18H14Cl4N2O.
What is the molecular weight of Miconazole?
The molecular weight of Miconazole is 413.98602 g/mol.
What are the applications of Miconazole?
Miconazole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Miconazole?
You can request a quote for Miconazole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Miconazole?
Yes, CoreyChem provides custom synthesis services for Miconazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.