Clotrimazole
TL;DR: Clotrimazole (CAS 23593-75-1) is a chemical compound with molecular formula C22H17ClN2 and molecular weight 344.10803 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(2-chlorophenyl)-diphenylmethyl]imidazole
Also Known As: clotrimazole, Lotrimin, Canesten, Mycelex, Mycosporin
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C22H17ClN2 |
| Molecular Weight | 344.10803 g/mol |
| XLogP | 5.0 |
| Topological Polar Surface Area (TPSA) | 17.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 4 |
| Exact Mass | 344.10803 Da |
| Heavy Atoms | 25 |
| Complexity | 396.0 |
| Melting Point | 148 |
| Solubility | 0.49 |
| SMILES | C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4 |
| InChIKey | VNFPBHJOKIVQEB-UHFFFAOYSA-N |
Product Description
Applications: Clotrimazole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Clotrimazole (CAS 23593-75-1) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Clotrimazole (CAS 23593-75-1) has the molecular formula C22H17ClN2 and a molecular weight of 344.11 g/mol. Reported properties include a solubility: 0.49. It is also known as clotrimazole and Lotrimin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Clotrimazole
Property Insights of Clotrimazole
The XLogP value of 5.0 indicates that Clotrimazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 17.8 Ų, Clotrimazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Clotrimazole has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Clotrimazole?
The CAS number of Clotrimazole is 23593-75-1.
What is the molecular formula of Clotrimazole?
The molecular formula of Clotrimazole is C22H17ClN2.
What is the molecular weight of Clotrimazole?
The molecular weight of Clotrimazole is 344.10803 g/mol.
What are the applications of Clotrimazole?
Clotrimazole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Clotrimazole (CAS 23593-75-1) with custom...
Where can I buy Clotrimazole?
You can request a quote for Clotrimazole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Clotrimazole?
Yes, CoreyChem provides custom synthesis services for Clotrimazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.