Tolnaftate
TL;DR: Tolnaftate (CAS 2398-96-1) is a chemical compound with molecular formula C19H17NOS and molecular weight 307.1031 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate
Also Known As: tolnaftate, Tolnaphthate, Tinactin, Tonoftal, Sporiline
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C19H17NOS |
| Molecular Weight | 307.1031 g/mol |
| XLogP | 5.5 |
| Topological Polar Surface Area (TPSA) | 44.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 307.1031 Da |
| Heavy Atoms | 22 |
| Complexity | 386.0 |
| Melting Point | 230.9 to 232.7 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 72 °F (NTP, 1992) |
| SMILES | CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2 |
| InChIKey | FUSNMLFNXJSCDI-UHFFFAOYSA-N |
Product Description
Applications: Tolnaftate is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Tolnaftate (CAS 2398-96-1) is a pharmaceutical intermediate with the molecular formula C19H17NOS and a molecular weight of 307.1 g/mol. Key physical properties include a solubility: less than 1 mg/mL at 72 °F (NTP, 1992). Synonyms include tolnaftate and Tolnaphthate.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Tolnaftate
Property Insights of Tolnaftate
The XLogP value of 5.5 indicates that Tolnaftate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.6 Ų, Tolnaftate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tolnaftate has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Tolnaftate?
The CAS number of Tolnaftate is 2398-96-1.
What is the molecular formula of Tolnaftate?
The molecular formula of Tolnaftate is C19H17NOS.
What is the molecular weight of Tolnaftate?
The molecular weight of Tolnaftate is 307.1031 g/mol.
What are the applications of Tolnaftate?
Tolnaftate is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton...
Where can I buy Tolnaftate?
You can request a quote for Tolnaftate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tolnaftate?
Yes, CoreyChem provides custom synthesis services for Tolnaftate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.