Sulfadoxine
TL;DR: Sulfadoxine (CAS 2447-57-6) is a chemical compound with molecular formula C12H14N4O4S and molecular weight 310.07358 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
Also Known As: SULFADOXINE, Sulphadoxine, Sulfadoxin, Sulforthomidine, Sulphormethoxine
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H14N4O4S |
| Molecular Weight | 310.07358 g/mol |
| XLogP | 0.7 |
| Topological Polar Surface Area (TPSA) | 125.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 310.07358 Da |
| Heavy Atoms | 21 |
| Complexity | 419.0 |
| Melting Point | 190-194 °C |
| Solubility | 2.96e-01 g/L |
| SMILES | COC1=C(N=CN=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N |
| InChIKey | PJSFRIWCGOHTNF-UHFFFAOYSA-N |
Chemical Property Profile of Sulfadoxine
Property Insights of Sulfadoxine
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Sulfadoxine. The TPSA of 125.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Sulfadoxine. Following Lipinski's Rule of Five, Sulfadoxine has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Sulfadoxine?
The CAS number of Sulfadoxine is 2447-57-6.
What is the molecular formula of Sulfadoxine?
The molecular formula of Sulfadoxine is C12H14N4O4S.
What is the molecular weight of Sulfadoxine?
The molecular weight of Sulfadoxine is 310.07358 g/mol.
Where can I buy Sulfadoxine?
You can request a quote for Sulfadoxine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Sulfadoxine?
Yes, CoreyChem provides custom synthesis services for Sulfadoxine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.