Nomifensine
TL;DR: Nomifensine (CAS 24526-64-5) is a chemical compound with molecular formula C16H18N2 and molecular weight 238.147 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine
Also Known As: Nomifensine, nomifensin, Linamiphen, Nomifensina, Nomifensinum
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H18N2 |
| Molecular Weight | 238.147 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 29.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 238.147 Da |
| Heavy Atoms | 18 |
| Complexity | 272.0 |
| Melting Point | 180 |
| SMILES | CN1CC(C2=C(C1)C(=CC=C2)N)C3=CC=CC=C3 |
| InChIKey | XXPANQJNYNUNES-UHFFFAOYSA-N |
Product Description
Applications: Nomifensine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nomifensine (CAS 24526-64-5) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Nomifensine is a pharmaceutical intermediate identified by CAS number 24526-64-5 and the molecular formula C16H18N2 and a molecular weight of 238.15 g/mol. It is also known as Nomifensine and nomifensin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nomifensine
Property Insights of Nomifensine
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nomifensine. With a topological polar surface area (TPSA) of 29.3 Ų, Nomifensine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nomifensine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nomifensine?
The CAS number of Nomifensine is 24526-64-5.
What is the molecular formula of Nomifensine?
The molecular formula of Nomifensine is C16H18N2.
What is the molecular weight of Nomifensine?
The molecular weight of Nomifensine is 238.147 g/mol.
What are the applications of Nomifensine?
Nomifensine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nomifensine (CAS 24526-64-5) with custom...
Where can I buy Nomifensine?
You can request a quote for Nomifensine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nomifensine?
Yes, CoreyChem provides custom synthesis services for Nomifensine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.