Trim
TL;DR: Trim (CAS 25371-96-4) is a chemical compound with molecular formula C10H7F3N2 and molecular weight 212.05614 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[2-(trifluoromethyl)phenyl]imidazole
Also Known As: Trim, 1-(2-Trifluoromethylphenyl)imidazole, 1-[2-(trifluoromethyl)phenyl]imidazole, 1-(2-(Trifluoromethyl)phenyl)-1H-imidazole, 1-TRIM
Application Areas
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H7F3N2 |
| Molecular Weight | 212.05614 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 17.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 212.05614 Da |
| Heavy Atoms | 15 |
| Complexity | 217.0 |
| Solubility | 30.2 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | C1=CC=C(C(=C1)C(F)(F)F)N2C=CN=C2 |
| InChIKey | WZBWBNCQUTXYEL-UHFFFAOYSA-N |
Product Description
Applications: Trim is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Trim is a pharmaceutical intermediate identified by CAS number 25371-96-4 and the molecular formula C10H7F3N2 and a molecular weight of 212.06 g/mol. Physically, the compound has a solubility: 30.2 [ug/mL] (The mean of the results at pH 7.4). Synonyms include Trim and 1-(2-Trifluoromethylphenyl)imidazole.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Trim
Property Insights of Trim
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trim. With a topological polar surface area (TPSA) of 17.8 Ų, Trim exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Trim has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Trim?
The CAS number of Trim is 25371-96-4.
What is the molecular formula of Trim?
The molecular formula of Trim is C10H7F3N2.
What is the molecular weight of Trim?
The molecular weight of Trim is 212.05614 g/mol.
What are the applications of Trim?
Trim is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis...
Where can I buy Trim?
You can request a quote for Trim directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Trim?
Yes, CoreyChem provides custom synthesis services for Trim and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.