cefazolin
TL;DR: cefazolin (CAS 25953-19-9) is a chemical compound with molecular formula C14H14N8O4S3 and molecular weight 454.03003 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Also Known As: cefazolin, Cephazolin, Elzogram, Cephamezine;Cephazoline, BAS 00911336
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H14N8O4S3 |
| Molecular Weight | 454.03003 g/mol |
| XLogP | -0.4 |
| Topological Polar Surface Area (TPSA) | 235.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 7 |
| Exact Mass | 454.03003 Da |
| Heavy Atoms | 29 |
| Complexity | 740.0 |
| Solubility | 49.7 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | CC1=NN=C(S1)SCC2=C(N3C(C(C3=O)NC(=O)CN4C=NN=N4)SC2)C(=O)O |
| InChIKey | MLYYVTUWGNIJIB-UHFFFAOYSA-N |
Chemical Property Profile of cefazolin
Property Insights of cefazolin
The XLogP value of -0.4 indicates that cefazolin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 235.0 Ų indicates high polarity, suggesting cefazolin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, cefazolin has 2 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of cefazolin?
The CAS number of cefazolin is 25953-19-9.
What is the molecular formula of cefazolin?
The molecular formula of cefazolin is C14H14N8O4S3.
What is the molecular weight of cefazolin?
The molecular weight of cefazolin is 454.03003 g/mol.
Where can I buy cefazolin?
You can request a quote for cefazolin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for cefazolin?
Yes, CoreyChem provides custom synthesis services for cefazolin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.