N-(2-Phenylethyl)indomethacin Amide
TL;DR: N-(2-Phenylethyl)indomethacin Amide (CAS 261766-32-9) is a chemical compound with molecular formula C27H25ClN2O3 and molecular weight 460.15536 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-(2-phenylethyl)acetamide
Also Known As: N-(2-Phenylethyl)indomethacin Amide, N-(2-phenylethyl)-Indomethacin amide, indomethacin phenethylamide, N-2PIA, Indomethacin derivative, 19
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C27H25ClN2O3 |
| Molecular Weight | 460.15536 g/mol |
| XLogP | 6.0 |
| Topological Polar Surface Area (TPSA) | 60.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 7 |
| Exact Mass | 460.15536 Da |
| Heavy Atoms | 33 |
| Complexity | 660.0 |
| SMILES | CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)NCCC4=CC=CC=C4 |
| InChIKey | VYDBTNADENXYSN-UHFFFAOYSA-N |
Chemical Property Profile of N-(2-Phenylethyl)indomethacin Amide
Property Insights of N-(2-Phenylethyl)indomethacin Amide
The XLogP value of 6.0 indicates that N-(2-Phenylethyl)indomethacin Amide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.3 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(2-Phenylethyl)indomethacin Amide. Following Lipinski's Rule of Five, N-(2-Phenylethyl)indomethacin Amide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of N-(2-Phenylethyl)indomethacin Amide?
The CAS number of N-(2-Phenylethyl)indomethacin Amide is 261766-32-9.
What is the molecular formula of N-(2-Phenylethyl)indomethacin Amide?
The molecular formula of N-(2-Phenylethyl)indomethacin Amide is C27H25ClN2O3.
What is the molecular weight of N-(2-Phenylethyl)indomethacin Amide?
The molecular weight of N-(2-Phenylethyl)indomethacin Amide is 460.15536 g/mol.
Where can I buy N-(2-Phenylethyl)indomethacin Amide?
You can request a quote for N-(2-Phenylethyl)indomethacin Amide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-(2-Phenylethyl)indomethacin Amide?
Yes, CoreyChem provides custom synthesis services for N-(2-Phenylethyl)indomethacin Amide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.