Zotepine
TL;DR: Zotepine (CAS 26615-21-4) is a chemical compound with molecular formula C18H18ClNOS and molecular weight 331.07977 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(3-chlorobenzo[b][1]benzothiepin-5-yl)oxy-N,N-dimethylethanamine
Also Known As: zotepine, Nipolept, Lodopin, Zotepina, Zoleptil
Application Areas
Top 5 of 11 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H18ClNOS |
| Molecular Weight | 331.07977 g/mol |
| XLogP | 4.8 |
| Topological Polar Surface Area (TPSA) | 37.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 331.07977 Da |
| Heavy Atoms | 22 |
| Complexity | 401.0 |
| Melting Point | 90ºC |
| Boiling Point | 478.4ºC |
| Solubility | Poorly soluble |
| SMILES | CN(C)CCOC1=CC2=CC=CC=C2SC3=C1C=C(C=C3)Cl |
| InChIKey | HDOZVRUNCMBHFH-UHFFFAOYSA-N |
Product Description
Applications: Zotepine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Zotepine (CAS 26615-21-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Zotepine (CAS 26615-21-4) has the molecular formula C18H18ClNOS and a molecular weight of 331.08 g/mol. Reported properties include a solubility: Poorly soluble. It is also known as zotepine and Nipolept.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Zotepine
Property Insights of Zotepine
The XLogP value of 4.8 indicates that Zotepine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.8 Ų, Zotepine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Zotepine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Zotepine?
The CAS number of Zotepine is 26615-21-4.
What is the molecular formula of Zotepine?
The molecular formula of Zotepine is C18H18ClNOS.
What is the molecular weight of Zotepine?
The molecular weight of Zotepine is 331.07977 g/mol.
What are the applications of Zotepine?
Zotepine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Zotepine (CAS 26615-21-4) with custom...
Where can I buy Zotepine?
You can request a quote for Zotepine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Zotepine?
Yes, CoreyChem provides custom synthesis services for Zotepine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.