Econazole
TL;DR: Econazole (CAS 27220-47-9) is a chemical compound with molecular formula C18H15Cl3N2O and molecular weight 380.025 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole
Also Known As: econazole, Ecostatin, Econazolum, Econazol, Econazole nitrate
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H15Cl3N2O |
| Molecular Weight | 380.025 g/mol |
| XLogP | 5.3 |
| Topological Polar Surface Area (TPSA) | 27.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 6 |
| Exact Mass | 380.025 Da |
| Heavy Atoms | 24 |
| Complexity | 379.0 |
| Melting Point | 162 |
| Solubility | 1.48e-03 g/L |
| SMILES | C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl |
| InChIKey | LEZWWPYKPKIXLL-UHFFFAOYSA-N |
Product Description
Applications: Econazole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Econazole (CAS 27220-47-9) has the molecular formula C18H15Cl3N2O and a molecular weight of 380.02 g/mol. Reported properties include a solubility: 1.48e-03 g/L. Synonyms include econazole and Ecostatin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Econazole
Property Insights of Econazole
The XLogP value of 5.3 indicates that Econazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 27.1 Ų, Econazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Econazole has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Econazole?
The CAS number of Econazole is 27220-47-9.
What is the molecular formula of Econazole?
The molecular formula of Econazole is C18H15Cl3N2O.
What is the molecular weight of Econazole?
The molecular weight of Econazole is 380.025 g/mol.
What are the applications of Econazole?
Econazole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Econazole?
You can request a quote for Econazole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Econazole?
Yes, CoreyChem provides custom synthesis services for Econazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.