Nigericin
TL;DR: Nigericin (CAS 28380-24-7) is a chemical compound with molecular formula C40H68O11 and molecular weight 724.47614 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2R)-2-[(2R,3S,6R)-6-[[(2S,4R,5R,6R,7R,9R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,4,6-trimethyl-1,10-dioxaspiro[4.5]decan-9-yl]methyl]-3-methyloxan-2-yl]propanoic acid
Also Known As: nigericin, Polyetherin A, Azalomycin M, Helixin C, Antibiotic X-464
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C40H68O11 |
| Molecular Weight | 724.47614 g/mol |
| XLogP | 5.5 |
| Topological Polar Surface Area (TPSA) | 142.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 9 |
| Exact Mass | 724.47614 Da |
| Heavy Atoms | 51 |
| Complexity | 1230.0 |
| SMILES | C[C@H]1CC[C@@H](O[C@H]1[C@@H](C)C(=O)O)C[C@@H]2C[C@H]([C@H]([C@@]3(O2)[C@@H](C[C@@](O3)(C)[C@H]4CC[C@@](O4)(C)[C@H]5[C@H](C[C@@H](O5)[C@@H]6[C@H](C[C@H]([C@@](O6)(CO)O)C)C)C)C)C)OC |
| InChIKey | DANUORFCFTYTSZ-SJSJOXFOSA-N |
Chemical Property Profile of Nigericin
Property Insights of Nigericin
The XLogP value of 5.5 indicates that Nigericin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 142.0 Ų indicates high polarity, suggesting Nigericin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Nigericin has 3 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Nigericin?
The CAS number of Nigericin is 28380-24-7.
What is the molecular formula of Nigericin?
The molecular formula of Nigericin is C40H68O11.
What is the molecular weight of Nigericin?
The molecular weight of Nigericin is 724.47614 g/mol.
Where can I buy Nigericin?
You can request a quote for Nigericin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nigericin?
Yes, CoreyChem provides custom synthesis services for Nigericin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.