Bumetanide
TL;DR: Bumetanide (CAS 28395-03-1) is a chemical compound with molecular formula C17H20N2O5S and molecular weight 364.10928 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
Also Known As: bumetanide, Bumex, Burinex, Fordiuran, Lunetoron
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H20N2O5S |
| Molecular Weight | 364.10928 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 127.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 364.10928 Da |
| Heavy Atoms | 25 |
| Complexity | 528.0 |
| Melting Point | 230-231 |
| Solubility | >20 mg/mL (in base) |
| SMILES | CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2 |
| InChIKey | MAEIEVLCKWDQJH-UHFFFAOYSA-N |
Chemical Property Profile of Bumetanide
Property Insights of Bumetanide
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Bumetanide. The TPSA of 127.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Bumetanide. Following Lipinski's Rule of Five, Bumetanide has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Bumetanide?
The CAS number of Bumetanide is 28395-03-1.
What is the molecular formula of Bumetanide?
The molecular formula of Bumetanide is C17H20N2O5S.
What is the molecular weight of Bumetanide?
The molecular weight of Bumetanide is 364.10928 g/mol.
Where can I buy Bumetanide?
You can request a quote for Bumetanide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Bumetanide?
Yes, CoreyChem provides custom synthesis services for Bumetanide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.