Guanfacine
TL;DR: Guanfacine (CAS 29110-47-2) is a chemical compound with molecular formula C9H9Cl2N3O and molecular weight 245.01227 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide
Also Known As: Guanfacina, Estulic, Intuniv, Guanfacinum, Tenex
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H9Cl2N3O |
| Molecular Weight | 245.01227 g/mol |
| XLogP | 2.0 |
| Topological Polar Surface Area (TPSA) | 81.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 245.01227 Da |
| Heavy Atoms | 15 |
| Complexity | 256.0 |
| Melting Point | 213-216 |
| Solubility | 1mg/mL |
| SMILES | C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl |
| InChIKey | INJOMKTZOLKMBF-UHFFFAOYSA-N |
Product Description
Applications: Guanfacine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Guanfacine (CAS 29110-47-2) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Guanfacine (CAS 29110-47-2) has the molecular formula C9H9Cl2N3O and a molecular weight of 245.01 g/mol. Reported properties include a solubility: 1mg/mL. It is also known as Guanfacina and Estulic.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Guanfacine
Property Insights of Guanfacine
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Guanfacine. The TPSA of 81.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Guanfacine. Following Lipinski's Rule of Five, Guanfacine has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Guanfacine?
The CAS number of Guanfacine is 29110-47-2.
What is the molecular formula of Guanfacine?
The molecular formula of Guanfacine is C9H9Cl2N3O.
What is the molecular weight of Guanfacine?
The molecular weight of Guanfacine is 245.01227 g/mol.
What are the applications of Guanfacine?
Guanfacine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Guanfacine (CAS 29110-47-2) with custom...
Where can I buy Guanfacine?
You can request a quote for Guanfacine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Guanfacine?
Yes, CoreyChem provides custom synthesis services for Guanfacine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.