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Norchlorcyclizine structure
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Norchlorcyclizine

TL;DR: Norchlorcyclizine (CAS 303-26-4) is a chemical compound with molecular formula C17H19ClN2 and molecular weight 286.1237 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.

1-[(4-chlorophenyl)-phenylmethyl]piperazine

Also Known As: Norchlorcyclizine, 1-(4-Chlorobenzhydryl)piperazine, 1-((4-chlorophenyl)(phenyl)methyl)piperazine, null, N-(p-Chlorobenzhydryl)piperazine

CAS Number
303-26-4
Molecular Formula
C17H19ClN2
Molecular Weight
286.1237 g/mol
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Application Areas

Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.

Agrochemicals (4 patents) Analytical Reagents (25 patents) Biotechnology (7 patents) Catalysts (4 patents) Heterocyclic Building Blocks (428 patents)

Technical Specifications

Molecular FormulaC17H19ClN2
Molecular Weight286.1237 g/mol
XLogP3.4
Topological Polar Surface Area (TPSA)15.3 Ų
Hydrogen Bond Donors1
Hydrogen Bond Acceptors2
Rotatable Bonds3
Exact Mass286.1237 Da
Heavy Atoms20
Complexity277.0
SMILESC1CN(CCN1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
InChIKeyUZKBSZSTDQSMDR-UHFFFAOYSA-N

Product Description

Applications: Norchlorcyclizine is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Norchlorcyclizine (CAS 303-26-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.

A heterocyclic building block supplied by CoreyChem, Norchlorcyclizine (CAS 303-26-4) has the molecular formula C17H19ClN2 and a molecular weight of 286.12 g/mol. It is also known as Norchlorcyclizine and 1-(4-Chlorobenzhydryl)piperazine.

Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.

Chemical Property Profile of Norchlorcyclizine

XLogP
3.4
TPSA (Topological Polar Surface Area)
15.3
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
3
Heavy Atoms
20
Complexity
277.0
Exact Mass
286.1237
Monoisotopic Mass
286.1237
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Norchlorcyclizine

The XLogP value of 3.4 indicates that Norchlorcyclizine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 15.3 Ų, Norchlorcyclizine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Norchlorcyclizine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the CAS number of Norchlorcyclizine?

The CAS number of Norchlorcyclizine is 303-26-4.

What is the molecular formula of Norchlorcyclizine?

The molecular formula of Norchlorcyclizine is C17H19ClN2.

What is the molecular weight of Norchlorcyclizine?

The molecular weight of Norchlorcyclizine is 286.1237 g/mol.

What are the applications of Norchlorcyclizine?

Norchlorcyclizine is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Norchlorcyclizine (CAS 303-26-4) with...

Where can I buy Norchlorcyclizine?

You can request a quote for Norchlorcyclizine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.

Does CoreyChem offer custom synthesis for Norchlorcyclizine?

Yes, CoreyChem provides custom synthesis services for Norchlorcyclizine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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