Clomipramine
TL;DR: Clomipramine (CAS 303-49-1) is a chemical compound with molecular formula C19H23ClN2 and molecular weight 314.15497 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
Also Known As: clomipramine, Chlorimipramine, Monochlorimipramine, 3-Chloroimipramine, Hydiphen
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C19H23ClN2 |
| Molecular Weight | 314.15497 g/mol |
| XLogP | 5.2 |
| Topological Polar Surface Area (TPSA) | 6.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 314.15497 Da |
| Heavy Atoms | 22 |
| Complexity | 346.0 |
| Melting Point | 191.5-192 |
| Boiling Point | 160-170 °C at 3.00E-01 mm Hg |
| Solubility | 0.294 |
| SMILES | CN(C)CCCN1C2=CC=CC=C2CCC3=C1C=C(C=C3)Cl |
| InChIKey | GDLIGKIOYRNHDA-UHFFFAOYSA-N |
Product Description
Applications: Clomipramine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Clomipramine is a pharmaceutical intermediate identified by CAS number 303-49-1 and the molecular formula C19H23ClN2 and a molecular weight of 314.15 g/mol. Physically, the compound has a solubility: 0.294. Synonyms include clomipramine and Chlorimipramine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Clomipramine
Property Insights of Clomipramine
The XLogP value of 5.2 indicates that Clomipramine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.5 Ų, Clomipramine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Clomipramine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Clomipramine?
The CAS number of Clomipramine is 303-49-1.
What is the molecular formula of Clomipramine?
The molecular formula of Clomipramine is C19H23ClN2.
What is the molecular weight of Clomipramine?
The molecular weight of Clomipramine is 314.15497 g/mol.
What are the applications of Clomipramine?
Clomipramine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Clomipramine?
You can request a quote for Clomipramine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Clomipramine?
Yes, CoreyChem provides custom synthesis services for Clomipramine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.