flunarizine
TL;DR: flunarizine (CAS 30484-77-6) is a chemical compound with molecular formula C26H28Cl2F2N2 and molecular weight 476.15976 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[bis(4-fluorophenyl)methyl]-4-(3-phenylprop-2-enyl)piperazine;dihydrochloride
Also Known As: flunarizine, Flunarizine 2HCl, flunarizine hydrochloride, Flunarizine dihydrochloride, Flunarizine * 2HCl
Application Areas
Top 5 of 7 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C26H28Cl2F2N2 |
| Molecular Weight | 476.15976 g/mol |
| XLogP | 6.23 |
| Topological Polar Surface Area (TPSA) | 6.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 476.15976 Da |
| Heavy Atoms | 32 |
| Complexity | 487.0 |
| SMILES | C1CN(CCN1CC=CC2=CC=CC=C2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl.Cl |
| InChIKey | RXKMOPXNWTYEHI-UHFFFAOYSA-N |
Chemical Property Profile of flunarizine
Property Insights of flunarizine
The XLogP value of 6.23 indicates that flunarizine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.5 Ų, flunarizine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, flunarizine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of flunarizine?
The CAS number of flunarizine is 30484-77-6.
What is the molecular formula of flunarizine?
The molecular formula of flunarizine is C26H28Cl2F2N2.
What is the molecular weight of flunarizine?
The molecular weight of flunarizine is 476.15976 g/mol.
Where can I buy flunarizine?
You can request a quote for flunarizine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for flunarizine?
Yes, CoreyChem provides custom synthesis services for flunarizine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.