Nocodazole
TL;DR: Nocodazole (CAS 31430-18-9) is a chemical compound with molecular formula C14H11N3O3S and molecular weight 301.05212 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate
Also Known As: nocodazole, Oncodazole, Nocodazol, Nocodazolum, Nocidazole
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H11N3O3S |
| Molecular Weight | 301.05212 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 112.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 301.05212 Da |
| Heavy Atoms | 21 |
| Complexity | 420.0 |
| Melting Point | 570 °F (decomposes) (NTP, 1992) |
| Solubility | less than 1 mg/mL at 59 °F (NTP, 1992) |
| SMILES | COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3 |
| InChIKey | KYRVNWMVYQXFEU-UHFFFAOYSA-N |
Product Description
Applications: Nocodazole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Nocodazole (CAS 31430-18-9) is a pharmaceutical intermediate with the molecular formula C14H11N3O3S and a molecular weight of 301.05 g/mol. Key physical properties include a solubility: less than 1 mg/mL at 59 °F (NTP, 1992). Synonyms include nocodazole and Oncodazole.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nocodazole
Property Insights of Nocodazole
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nocodazole. The TPSA of 112.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Nocodazole. Following Lipinski's Rule of Five, Nocodazole has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nocodazole?
The CAS number of Nocodazole is 31430-18-9.
What is the molecular formula of Nocodazole?
The molecular formula of Nocodazole is C14H11N3O3S.
What is the molecular weight of Nocodazole?
The molecular weight of Nocodazole is 301.05212 g/mol.
What are the applications of Nocodazole?
Nocodazole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Nocodazole?
You can request a quote for Nocodazole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nocodazole?
Yes, CoreyChem provides custom synthesis services for Nocodazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.