Diazomethane
TL;DR: Diazomethane (CAS 334-88-3) is a chemical compound with molecular formula CH2N2 and molecular weight 42.021797 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
diazomethane
Also Known As: DIAZOMETHANE, Azimethylene, Acomethylene, Diazirine, Methane, diazo-
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | CH2N2 |
| Molecular Weight | 42.021797 g/mol |
| XLogP | 1.6 |
| Topological Polar Surface Area (TPSA) | 2.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 42.021797 Da |
| Heavy Atoms | 3 |
| Complexity | 25.0 |
| Melting Point | -229 °F (NIOSH, 2024) |
| Boiling Point | -9 °F at 760 mmHg (NIOSH, 2024) |
| Density | 1.45 |
| Flash Point | Flammable gas |
| Vapor Pressure | greater than 1 atm (NIOSH, 2024) |
| Solubility | Reacts with water (NIOSH, 2024) |
| SMILES | C=[N+]=[N-] |
| InChIKey | YXHKONLOYHBTNS-UHFFFAOYSA-N |
Product Description
Applications: Diazomethane is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Diazomethane (CAS 334-88-3) is a heterocyclic building block with the molecular formula CH2N2 and a molecular weight of 42.02 g/mol. Key physical properties include a density of 1.45 g/cm³, a solubility: Reacts with water (NIOSH, 2024). Synonyms include DIAZOMETHANE and Azimethylene.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Diazomethane
Property Insights of Diazomethane
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Diazomethane. With a topological polar surface area (TPSA) of 2.0 Ų, Diazomethane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Diazomethane has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Diazomethane?
The CAS number of Diazomethane is 334-88-3.
What is the molecular formula of Diazomethane?
The molecular formula of Diazomethane is CH2N2.
What is the molecular weight of Diazomethane?
The molecular weight of Diazomethane is 42.021797 g/mol.
What are the applications of Diazomethane?
Diazomethane is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Diazomethane?
You can request a quote for Diazomethane directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Diazomethane?
Yes, CoreyChem provides custom synthesis services for Diazomethane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.