Chlorobis(dimethylamino)phosphine
TL;DR: Chlorobis(dimethylamino)phosphine (CAS 3348-44-5) is a chemical compound with molecular formula C4H12ClN2P and molecular weight 154.04266 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[chloro(dimethylamino)phosphanyl]-N-methylmethanamine
Also Known As: Bis(dimethylamino)chlorophosphine, Chlorobis(dimethylamino)phosphine, ((CH3)2N)2PCl, P(NMe2)2Cl, BIS CHLOROPHOSPHINE
Application Areas
Top 5 of 8 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C4H12ClN2P |
| Molecular Weight | 154.04266 g/mol |
| XLogP | 1.2 |
| Topological Polar Surface Area (TPSA) | 6.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 154.04266 Da |
| Heavy Atoms | 8 |
| Complexity | 59.0 |
| SMILES | CN(C)P(N(C)C)Cl |
| InChIKey | MAJFLEHNBOUSIY-UHFFFAOYSA-N |
Product Description
Applications: Chlorobis(dimethylamino)phosphine is used in organometallic chemistry, cross-coupling reactions, and metal-mediated transformations, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Chlorobis(dimethylamino)phosphine is a organometallic reagent identified by CAS number 3348-44-5 and the molecular formula C4H12ClN2P and a molecular weight of 154.04 g/mol. Synonyms include Bis(dimethylamino)chlorophosphine and Chlorobis(dimethylamino)phosphine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Chlorobis(dimethylamino)phosphine
Property Insights of Chlorobis(dimethylamino)phosphine
The XLogP value of 1.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Chlorobis(dimethylamino)phosphine. With a topological polar surface area (TPSA) of 6.5 Ų, Chlorobis(dimethylamino)phosphine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Chlorobis(dimethylamino)phosphine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Chlorobis(dimethylamino)phosphine?
The CAS number of Chlorobis(dimethylamino)phosphine is 3348-44-5.
What is the molecular formula of Chlorobis(dimethylamino)phosphine?
The molecular formula of Chlorobis(dimethylamino)phosphine is C4H12ClN2P.
What is the molecular weight of Chlorobis(dimethylamino)phosphine?
The molecular weight of Chlorobis(dimethylamino)phosphine is 154.04266 g/mol.
What are the applications of Chlorobis(dimethylamino)phosphine?
Chlorobis(dimethylamino)phosphine is used in organometallic chemistry, cross-coupling reactions, and metal-mediated transformations, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis....
Where can I buy Chlorobis(dimethylamino)phosphine?
You can request a quote for Chlorobis(dimethylamino)phosphine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Chlorobis(dimethylamino)phosphine?
Yes, CoreyChem provides custom synthesis services for Chlorobis(dimethylamino)phosphine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.