Clotiazepam
TL;DR: Clotiazepam (CAS 33671-46-4) is a chemical compound with molecular formula C16H15ClN2OS and molecular weight 318.05936 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-(2-chlorophenyl)-7-ethyl-1-methyl-3H-thieno[2,3-e][1,4]diazepin-2-one
Also Known As: clotiazepam, Rize, Trecalmo, Rizen, Tienor
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H15ClN2OS |
| Molecular Weight | 318.05936 g/mol |
| XLogP | 3.5 |
| Topological Polar Surface Area (TPSA) | 60.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 318.05936 Da |
| Heavy Atoms | 21 |
| Complexity | 442.0 |
| Melting Point | 105-106 |
| Solubility | 5.37e-03 g/L |
| SMILES | CCC1=CC2=C(S1)N(C(=O)CN=C2C3=CC=CC=C3Cl)C |
| InChIKey | CHBRHODLKOZEPZ-UHFFFAOYSA-N |
Product Description
Applications: Clotiazepam is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Clotiazepam (CAS 33671-46-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Clotiazepam (CAS 33671-46-4) has the molecular formula C16H15ClN2OS and a molecular weight of 318.06 g/mol. Reported properties include a solubility: 5.37e-03 g/L. It is also known as clotiazepam and Rize.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Clotiazepam
Property Insights of Clotiazepam
The XLogP value of 3.5 indicates that Clotiazepam is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Clotiazepam. Following Lipinski's Rule of Five, Clotiazepam has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Clotiazepam?
The CAS number of Clotiazepam is 33671-46-4.
What is the molecular formula of Clotiazepam?
The molecular formula of Clotiazepam is C16H15ClN2OS.
What is the molecular weight of Clotiazepam?
The molecular weight of Clotiazepam is 318.05936 g/mol.
What are the applications of Clotiazepam?
Clotiazepam is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Clotiazepam (CAS 33671-46-4) with custom...
Where can I buy Clotiazepam?
You can request a quote for Clotiazepam directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Clotiazepam?
Yes, CoreyChem provides custom synthesis services for Clotiazepam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.