Temephos
TL;DR: Temephos (CAS 3383-96-8) is a chemical compound with molecular formula C16H20O6P2S3 and molecular weight 465.98972 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[4-(4-dimethoxyphosphinothioyloxyphenyl)sulfanylphenoxy]-dimethoxy-sulfanylidene-λ5-phosphane
Also Known As: temephos, Temefos, Difos, Difenphos, Abathion
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H20O6P2S3 |
| Molecular Weight | 465.98972 g/mol |
| XLogP | 6.0 |
| Topological Polar Surface Area (TPSA) | 145.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 10 |
| Exact Mass | 465.98972 Da |
| Heavy Atoms | 27 |
| Complexity | 474.0 |
| Melting Point | 87 °F (NIOSH, 2024) |
| Boiling Point | 248 to 257 °F at 760 mmHg (Decomposes) (NIOSH, 2024) |
| Density | 1.32 (NIOSH, 2024) - Denser than water; will sink |
| Flash Point | ABATE 4-E 167 °F (Closed Cup); ABATE 6-E 109 °F (Closed Cup); ABATE 200-E 113 °F (Closed Cup); ABATE 500-E 142 °F (Closed Cup) |
| Vapor Pressure | 7e-08 mmHg at 77 °F (NIOSH, 2024) |
| Solubility | Insoluble (NIOSH, 2024) |
| SMILES | COP(=S)(OC)OC1=CC=C(C=C1)SC2=CC=C(C=C2)OP(=S)(OC)OC |
| InChIKey | WWJZWCUNLNYYAU-UHFFFAOYSA-N |
Product Description
Applications: Temephos is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as agrochemical development, including crop protection agent synthesis. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Temephos (CAS 3383-96-8) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Temephos (CAS 3383-96-8) is a heterocyclic building block with the molecular formula C16H20O6P2S3 and a molecular weight of 465.99 g/mol. Key physical properties include a density of 1.32 (NIOSH, 2024) - Denser than water; will sink g/cm³, a solubility: Insoluble (NIOSH, 2024). It is also known as temephos and Temefos.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Temephos
Property Insights of Temephos
The XLogP value of 6.0 indicates that Temephos is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 145.0 Ų indicates high polarity, suggesting Temephos may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Temephos has 0 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Temephos?
The CAS number of Temephos is 3383-96-8.
What is the molecular formula of Temephos?
The molecular formula of Temephos is C16H20O6P2S3.
What is the molecular weight of Temephos?
The molecular weight of Temephos is 465.98972 g/mol.
What are the applications of Temephos?
Temephos is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as agrochemical development, including crop protection agent synthesis. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Temephos (CAS 3383-96-8) with...
Where can I buy Temephos?
You can request a quote for Temephos directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Temephos?
Yes, CoreyChem provides custom synthesis services for Temephos and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.