Orphenadrine Hydrochloride
TL;DR: Orphenadrine Hydrochloride (CAS 341-69-5) is a chemical compound with molecular formula C18H24ClNO and molecular weight 305.15463 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N,N-dimethyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine;hydrochloride
Also Known As: Orphenadrine hydrochloride, Orphenadrine HCl, Disipal, Mephenamin, Mebedrol
Application Areas
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H24ClNO |
| Molecular Weight | 305.15463 g/mol |
| XLogP | 4.08 |
| Topological Polar Surface Area (TPSA) | 12.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 6 |
| Exact Mass | 305.15463 Da |
| Heavy Atoms | 21 |
| Complexity | 260.0 |
| Melting Point | 313 to 315 °F (NTP, 1992) |
| Solubility | greater than or equal to 100 mg/mL at 66 °F (NTP, 1992) |
| SMILES | CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C.Cl |
| InChIKey | UQZKYYIKWZOKKD-UHFFFAOYSA-N |
Product Description
Applications: Orphenadrine Hydrochloride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Orphenadrine Hydrochloride (CAS 341-69-5) has the molecular formula C18H24ClNO and a molecular weight of 305.15 g/mol. Reported properties include a solubility: greater than or equal to 100 mg/mL at 66 °F (NTP, 1992). Synonyms include Orphenadrine hydrochloride and Orphenadrine HCl.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Orphenadrine Hydrochloride
Property Insights of Orphenadrine Hydrochloride
The XLogP value of 4.08 indicates that Orphenadrine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.5 Ų, Orphenadrine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Orphenadrine Hydrochloride has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Orphenadrine Hydrochloride?
The CAS number of Orphenadrine Hydrochloride is 341-69-5.
What is the molecular formula of Orphenadrine Hydrochloride?
The molecular formula of Orphenadrine Hydrochloride is C18H24ClNO.
What is the molecular weight of Orphenadrine Hydrochloride?
The molecular weight of Orphenadrine Hydrochloride is 305.15463 g/mol.
What are the applications of Orphenadrine Hydrochloride?
Orphenadrine Hydrochloride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item...
Where can I buy Orphenadrine Hydrochloride?
You can request a quote for Orphenadrine Hydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Orphenadrine Hydrochloride?
Yes, CoreyChem provides custom synthesis services for Orphenadrine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.