4-Fluorobenzenesulfonyl chloride
TL;DR: 4-Fluorobenzenesulfonyl chloride (CAS 349-88-2) is a chemical compound with molecular formula C6H4ClFO2S and molecular weight 193.96045 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-fluorobenzenesulfonyl chloride
Also Known As: 4-Fluorobenzenesulfonyl chloride, 4-Fluorobenzene-1-Sulfonyl Chloride, 4-Fluorobenzenesulphonyl chloride, null, p-Fluorobenzenesulfonyl chloride
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H4ClFO2S |
| Molecular Weight | 193.96045 g/mol |
| XLogP | 2.0 |
| Topological Polar Surface Area (TPSA) | 42.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 193.96045 Da |
| Heavy Atoms | 11 |
| Complexity | 213.0 |
| SMILES | C1=CC(=CC=C1F)S(=O)(=O)Cl |
| InChIKey | BFXHJFKKRGVUMU-UHFFFAOYSA-N |
Product Description
Applications: 4-Fluorobenzenesulfonyl chloride is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A heterocyclic building block supplied by CoreyChem, 4-Fluorobenzenesulfonyl chloride (CAS 349-88-2) has the molecular formula C6H4ClFO2S and a molecular weight of 193.96 g/mol. Synonyms include 4-Fluorobenzenesulfonyl chloride and 4-Fluorobenzene-1-Sulfonyl Chloride.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 4-Fluorobenzenesulfonyl chloride
Property Insights of 4-Fluorobenzenesulfonyl chloride
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Fluorobenzenesulfonyl chloride. With a topological polar surface area (TPSA) of 42.5 Ų, 4-Fluorobenzenesulfonyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Fluorobenzenesulfonyl chloride has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-Fluorobenzenesulfonyl chloride?
The CAS number of 4-Fluorobenzenesulfonyl chloride is 349-88-2.
What is the molecular formula of 4-Fluorobenzenesulfonyl chloride?
The molecular formula of 4-Fluorobenzenesulfonyl chloride is C6H4ClFO2S.
What is the molecular weight of 4-Fluorobenzenesulfonyl chloride?
The molecular weight of 4-Fluorobenzenesulfonyl chloride is 193.96045 g/mol.
What are the applications of 4-Fluorobenzenesulfonyl chloride?
4-Fluorobenzenesulfonyl chloride is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog...
Where can I buy 4-Fluorobenzenesulfonyl chloride?
You can request a quote for 4-Fluorobenzenesulfonyl chloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-Fluorobenzenesulfonyl chloride?
Yes, CoreyChem provides custom synthesis services for 4-Fluorobenzenesulfonyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.