Bupropion
TL;DR: Bupropion (CAS 34911-55-2) is a chemical compound with molecular formula C13H18ClNO and molecular weight 239.1077 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
Also Known As: bupropion, Amfebutamone, Amfebutamon, Wellbutrin, amfebutamonum
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C13H18ClNO |
| Molecular Weight | 239.1077 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 239.1077 Da |
| Heavy Atoms | 16 |
| Complexity | 247.0 |
| Melting Point | 233-234 °C |
| Boiling Point | BP: 52 °C at 0.005 mm Hg |
| Solubility | 312 |
| SMILES | CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C |
| InChIKey | SNPPWIUOZRMYNY-UHFFFAOYSA-N |
Product Description
Applications: Bupropion is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Bupropion (CAS 34911-55-2) has the molecular formula C13H18ClNO and a molecular weight of 239.11 g/mol. Reported properties include a solubility: 312. Synonyms include bupropion and Amfebutamone.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Bupropion
Property Insights of Bupropion
The XLogP value of 3.2 indicates that Bupropion is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, Bupropion exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Bupropion has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Bupropion?
The CAS number of Bupropion is 34911-55-2.
What is the molecular formula of Bupropion?
The molecular formula of Bupropion is C13H18ClNO.
What is the molecular weight of Bupropion?
The molecular weight of Bupropion is 239.1077 g/mol.
What are the applications of Bupropion?
Bupropion is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Bupropion?
You can request a quote for Bupropion directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Bupropion?
Yes, CoreyChem provides custom synthesis services for Bupropion and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.