diltiazem
TL;DR: diltiazem (CAS 34933-06-7) is a chemical compound with molecular formula C22H26N2O4S and molecular weight 414.16132 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate
Also Known As: diltiazem, Dilacor XR, Bosutinib, Cardizem, Diltiazem-d6
Application Areas
Top 5 of 9 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C22H26N2O4S |
| Molecular Weight | 414.16132 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 84.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 414.16132 Da |
| Heavy Atoms | 29 |
| Complexity | 565.0 |
| SMILES | CC(=O)OC1C(SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC |
| InChIKey | HSUGRBWQSSZJOP-UHFFFAOYSA-N |
Product Description
Applications: diltiazem is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
diltiazem (CAS 34933-06-7) is a pharmaceutical intermediate with the molecular formula C22H26N2O4S and a molecular weight of 414.16 g/mol. Synonyms include diltiazem and Dilacor XR.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of diltiazem
Property Insights of diltiazem
The XLogP value of 3.1 indicates that diltiazem is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 84.4 Ų falls within the moderate polarity range, balancing permeability and solubility for diltiazem. Following Lipinski's Rule of Five, diltiazem has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of diltiazem?
The CAS number of diltiazem is 34933-06-7.
What is the molecular formula of diltiazem?
The molecular formula of diltiazem is C22H26N2O4S.
What is the molecular weight of diltiazem?
The molecular weight of diltiazem is 414.16132 g/mol.
What are the applications of diltiazem?
diltiazem is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy diltiazem?
You can request a quote for diltiazem directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for diltiazem?
Yes, CoreyChem provides custom synthesis services for diltiazem and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.