N-(4-fluorophenyl)acetamide
TL;DR: N-(4-fluorophenyl)acetamide (CAS 351-83-7) is a chemical compound with molecular formula C8H8FNO and molecular weight 153.05899 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(4-fluorophenyl)acetamide
Also Known As: 4-Fluoroacetanilide, 4'-Fluoroacetanilide, N-(4-FLUOROPHENYL)ACETAMIDE, p-Fluoroacetanilide, Acetanilide, 4'-fluoro-
Application Areas
Top 5 of 8 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H8FNO |
| Molecular Weight | 153.05899 g/mol |
| XLogP | 1.5 |
| Topological Polar Surface Area (TPSA) | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 153.05899 Da |
| Heavy Atoms | 11 |
| Complexity | 141.0 |
| SMILES | CC(=O)NC1=CC=C(C=C1)F |
| InChIKey | JHEFOJNPLXSWNZ-UHFFFAOYSA-N |
Product Description
Applications: N-(4-fluorophenyl)acetamide is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
N-(4-fluorophenyl)acetamide is a heterocyclic building block identified by CAS number 351-83-7 and the molecular formula C8H8FNO and a molecular weight of 153.06 g/mol. Synonyms include 4-Fluoroacetanilide and 4'-Fluoroacetanilide.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of N-(4-fluorophenyl)acetamide
Property Insights of N-(4-fluorophenyl)acetamide
The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(4-fluorophenyl)acetamide. With a topological polar surface area (TPSA) of 29.1 Ų, N-(4-fluorophenyl)acetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(4-fluorophenyl)acetamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-(4-fluorophenyl)acetamide?
The CAS number of N-(4-fluorophenyl)acetamide is 351-83-7.
What is the molecular formula of N-(4-fluorophenyl)acetamide?
The molecular formula of N-(4-fluorophenyl)acetamide is C8H8FNO.
What is the molecular weight of N-(4-fluorophenyl)acetamide?
The molecular weight of N-(4-fluorophenyl)acetamide is 153.05899 g/mol.
What are the applications of N-(4-fluorophenyl)acetamide?
N-(4-fluorophenyl)acetamide is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item...
Where can I buy N-(4-fluorophenyl)acetamide?
You can request a quote for N-(4-fluorophenyl)acetamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-(4-fluorophenyl)acetamide?
Yes, CoreyChem provides custom synthesis services for N-(4-fluorophenyl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.