Bromhexine
TL;DR: Bromhexine (CAS 3572-43-8) is a chemical compound with molecular formula C14H20Br2N2 and molecular weight 373.99933 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline
Also Known As: bromhexine, Bromhexina, Bromexine, Bromhexinum, Fluibron
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H20Br2N2 |
| Molecular Weight | 373.99933 g/mol |
| XLogP | 4.3 |
| Topological Polar Surface Area (TPSA) | 29.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 375.99728 Da |
| Heavy Atoms | 18 |
| Complexity | 256.0 |
| Melting Point | 232-235 |
| Boiling Point | 413.8 |
| Solubility | <1 mg/mL |
| SMILES | CN(CC1=C(C(=CC(=C1)Br)Br)N)C2CCCCC2 |
| InChIKey | OJGDCBLYJGHCIH-UHFFFAOYSA-N |
Product Description
Applications: Bromhexine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Bromhexine is a pharmaceutical intermediate identified by CAS number 3572-43-8 and the molecular formula C14H20Br2N2 and a molecular weight of 374 g/mol. Physically, the compound has a solubility: <1 mg/mL. Synonyms include bromhexine and Bromhexina.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Bromhexine
Property Insights of Bromhexine
The XLogP value of 4.3 indicates that Bromhexine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.3 Ų, Bromhexine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Bromhexine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Bromhexine?
The CAS number of Bromhexine is 3572-43-8.
What is the molecular formula of Bromhexine?
The molecular formula of Bromhexine is C14H20Br2N2.
What is the molecular weight of Bromhexine?
The molecular weight of Bromhexine is 373.99933 g/mol.
What are the applications of Bromhexine?
Bromhexine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Bromhexine?
You can request a quote for Bromhexine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Bromhexine?
Yes, CoreyChem provides custom synthesis services for Bromhexine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.