Dexamethasone 21-sulfate
TL;DR: Dexamethasone 21-sulfate (CAS 36493-04-6) is a chemical compound with molecular formula C22H29FO8S and molecular weight 472.1567 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[2-[(8S,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] hydrogen sulfate
Also Known As: Dexamethasone 21-sulfate, KST-1A4374, 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione mono(hydrogen sulphate), (8S,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-17-(2-sulfooxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene, (9xi,11
Technical Specifications
| Molecular Formula | C22H29FO8S |
| Molecular Weight | 472.1567 g/mol |
| XLogP | 0.8 |
| Topological Polar Surface Area (TPSA) | 147.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 472.1567 Da |
| Heavy Atoms | 32 |
| Complexity | 1030.0 |
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4(C3([C@H](C[C@@]2([C@]1(C(=O)COS(=O)(=O)O)O)C)O)F)C |
| InChIKey | URGVZGFGWFYRGP-ZCWWIVCJSA-N |
Chemical Property Profile of Dexamethasone 21-sulfate
Property Insights of Dexamethasone 21-sulfate
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Dexamethasone 21-sulfate. The TPSA of 147.0 Ų indicates high polarity, suggesting Dexamethasone 21-sulfate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Dexamethasone 21-sulfate has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Dexamethasone 21-sulfate?
The CAS number of Dexamethasone 21-sulfate is 36493-04-6.
What is the molecular formula of Dexamethasone 21-sulfate?
The molecular formula of Dexamethasone 21-sulfate is C22H29FO8S.
What is the molecular weight of Dexamethasone 21-sulfate?
The molecular weight of Dexamethasone 21-sulfate is 472.1567 g/mol.
Where can I buy Dexamethasone 21-sulfate?
You can request a quote for Dexamethasone 21-sulfate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Dexamethasone 21-sulfate?
Yes, CoreyChem provides custom synthesis services for Dexamethasone 21-sulfate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.