Quazepam
TL;DR: Quazepam (CAS 36735-22-5) is a chemical compound with molecular formula C17H11ClF4N2S and molecular weight 386.02676 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepine-2-thione
Also Known As: quazepam, Doral, Selepam, Dormalin, Prosedar
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H11ClF4N2S |
| Molecular Weight | 386.02676 g/mol |
| XLogP | 4.0 |
| Topological Polar Surface Area (TPSA) | 47.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 386.02676 Da |
| Heavy Atoms | 25 |
| Complexity | 539.0 |
| Melting Point | 137.5-139 °C |
| Solubility | Insoluble |
| SMILES | C1C(=S)N(C2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F)CC(F)(F)F |
| InChIKey | IKMPWMZBZSAONZ-UHFFFAOYSA-N |
Product Description
Applications: Quazepam is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Quazepam (CAS 36735-22-5) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Quazepam (CAS 36735-22-5) has the molecular formula C17H11ClF4N2S and a molecular weight of 386.03 g/mol. Reported properties include a solubility: Insoluble. It is also known as quazepam and Doral.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Quazepam
Property Insights of Quazepam
The XLogP value of 4.0 indicates that Quazepam is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.7 Ų, Quazepam exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Quazepam has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Quazepam?
The CAS number of Quazepam is 36735-22-5.
What is the molecular formula of Quazepam?
The molecular formula of Quazepam is C17H11ClF4N2S.
What is the molecular weight of Quazepam?
The molecular weight of Quazepam is 386.02676 g/mol.
What are the applications of Quazepam?
Quazepam is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Quazepam (CAS 36735-22-5) with custom...
Where can I buy Quazepam?
You can request a quote for Quazepam directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Quazepam?
Yes, CoreyChem provides custom synthesis services for Quazepam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.