![(5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one structure](/static/products/369/369396-40-7.webp)
(5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one
TL;DR: (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one (CAS 369396-40-7) is a chemical compound with molecular formula C18H22N2O2S and molecular weight 330.1402 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(5E)-2-piperidin-1-yl-5-[(2-propan-2-yloxyphenyl)methylidene]-1,3-thiazol-4-one
Also Known As: (E)-5-(2-isopropoxybenzylidene)-2-(piperidin-1-yl)thiazol-4(5H)-one, (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one, (5E)-2-piperidin-1-yl-5-[(2-propan-2-yloxyphenyl)methylidene]-1,3-thiazol-4-one
Technical Specifications
| Molecular Formula | C18H22N2O2S |
| Molecular Weight | 330.1402 g/mol |
| XLogP | 4.1 |
| Topological Polar Surface Area (TPSA) | 67.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 330.1402 Da |
| Heavy Atoms | 23 |
| Complexity | 495.0 |
| SMILES | CC(C)OC1=CC=CC=C1/C=C/2\C(=O)N=C(S2)N3CCCCC3 |
| InChIKey | LIGPHZVOOQDFAE-FOWTUZBSSA-N |
Product Description
Applications: (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one is used in organic synthesis and process chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one (CAS 369396-40-7) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
(5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one is a fine chemical identified by CAS number 369396-40-7 and the molecular formula C18H22N2O2S and a molecular weight of 330.14 g/mol. It is also known as (E)-5-(2-isopropoxybenzylidene)-2-(piperidin-1-yl)thiazol-4(5H)-one and (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one.
CoreyChem provides it with COA documentation, and custom synthesis from milligram to multi-kilogram scales is available on request. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one
Property Insights of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one
The XLogP value of 4.1 indicates that (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.2 Ų falls within the moderate polarity range, balancing permeability and solubility for (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one. Following Lipinski's Rule of Five, (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one?
The CAS number of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one is 369396-40-7.
What is the molecular formula of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one?
The molecular formula of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one is C18H22N2O2S.
What is the molecular weight of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one?
The molecular weight of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one is 330.1402 g/mol.
What are the applications of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one?
(5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one is used in organic synthesis and process chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies...
Where can I buy (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one?
You can request a quote for (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one?
Yes, CoreyChem provides custom synthesis services for (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.