Difluoroacetic acid
TL;DR: Difluoroacetic acid (CAS 381-73-7) is a chemical compound with molecular formula C2H2F2O2 and molecular weight 96.00229 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,2-difluoroacetic acid
Also Known As: DIFLUOROACETIC ACID, 2,2-Difluoroacetic acid, Acetic acid, difluoro-, Difluoressigsaeure, 1,1-difluoroacetic acid
Application Areas
Top 5 of 19 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C2H2F2O2 |
| Molecular Weight | 96.00229 g/mol |
| XLogP | 0.6 |
| Topological Polar Surface Area (TPSA) | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 96.00229 Da |
| Heavy Atoms | 6 |
| Complexity | 60.0 |
| SMILES | C(C(=O)O)(F)F |
| InChIKey | PBWZKZYHONABLN-UHFFFAOYSA-N |
Product Description
Applications: Difluoroacetic acid is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Difluoroacetic acid (CAS 381-73-7) is a heterocyclic building block with the molecular formula C2H2F2O2 and a molecular weight of 96 g/mol. Synonyms include DIFLUOROACETIC ACID and 2,2-Difluoroacetic acid.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Difluoroacetic acid
Property Insights of Difluoroacetic acid
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Difluoroacetic acid. With a topological polar surface area (TPSA) of 37.3 Ų, Difluoroacetic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Difluoroacetic acid has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Difluoroacetic acid?
The CAS number of Difluoroacetic acid is 381-73-7.
What is the molecular formula of Difluoroacetic acid?
The molecular formula of Difluoroacetic acid is C2H2F2O2.
What is the molecular weight of Difluoroacetic acid?
The molecular weight of Difluoroacetic acid is 96.00229 g/mol.
What are the applications of Difluoroacetic acid?
Difluoroacetic acid is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Difluoroacetic acid?
You can request a quote for Difluoroacetic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Difluoroacetic acid?
Yes, CoreyChem provides custom synthesis services for Difluoroacetic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.