sulindac
TL;DR: sulindac (CAS 38194-50-2) is a chemical compound with molecular formula C20H17FO3S and molecular weight 356.08826 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl]acetic acid
Also Known As: sulindac, Aflodac, Clinoril, Sulreuma, Sulindac sulfoxide
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C20H17FO3S |
| Molecular Weight | 356.08826 g/mol |
| XLogP | 3.4 |
| Topological Polar Surface Area (TPSA) | 73.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 356.08826 Da |
| Heavy Atoms | 25 |
| Complexity | 616.0 |
| SMILES | CC1=C(C2=C(C1=CC3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O |
| InChIKey | MLKXDPUZXIRXEP-UHFFFAOYSA-N |
Product Description
Applications: sulindac is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
sulindac (CAS 38194-50-2) is a pharmaceutical intermediate with the molecular formula C20H17FO3S and a molecular weight of 356.09 g/mol. Synonyms include sulindac and Aflodac.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of sulindac
Property Insights of sulindac
The XLogP value of 3.4 indicates that sulindac is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.6 Ų falls within the moderate polarity range, balancing permeability and solubility for sulindac. Following Lipinski's Rule of Five, sulindac has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of sulindac?
The CAS number of sulindac is 38194-50-2.
What is the molecular formula of sulindac?
The molecular formula of sulindac is C20H17FO3S.
What is the molecular weight of sulindac?
The molecular weight of sulindac is 356.08826 g/mol.
What are the applications of sulindac?
sulindac is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy sulindac?
You can request a quote for sulindac directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for sulindac?
Yes, CoreyChem provides custom synthesis services for sulindac and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.