p-Nitrophenyl-2-aminothiazol-5-ylsulphone
TL;DR: p-Nitrophenyl-2-aminothiazol-5-ylsulphone (CAS 39565-05-4) is a chemical compound with molecular formula C9H7N3O4S2 and molecular weight 284.9878 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-amine
Also Known As: 2-Amino-5-(4-nitrophenylsulfonyl)thiazole, Picumast, 2-Amino-5-(p-nitrophenylsulfonyl)thiazole, 2-Amino-5-(p-nitrobenzenesulfonyl)thiazole, 5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-amine
Application Areas
Top 5 of 9 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H7N3O4S2 |
| Molecular Weight | 284.9878 g/mol |
| XLogP | 1.6 |
| Topological Polar Surface Area (TPSA) | 155.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 284.9878 Da |
| Heavy Atoms | 18 |
| Complexity | 409.0 |
| SMILES | C1=CC(=CC=C1[N+](=O)[O-])S(=O)(=O)C2=CN=C(S2)N |
| InChIKey | GKTKCGAOXFHFTD-UHFFFAOYSA-N |
Product Description
Applications: p-Nitrophenyl-2-aminothiazol-5-ylsulphone is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies p-Nitrophenyl-2-aminothiazol-5-ylsulphone (CAS 39565-05-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A heterocyclic building block supplied by CoreyChem, p-Nitrophenyl-2-aminothiazol-5-ylsulphone (CAS 39565-05-4) has the molecular formula C9H7N3O4S2 and a molecular weight of 284.99 g/mol. It is also known as 2-Amino-5-(4-nitrophenylsulfonyl)thiazole and Picumast.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of p-Nitrophenyl-2-aminothiazol-5-ylsulphone
Property Insights of p-Nitrophenyl-2-aminothiazol-5-ylsulphone
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for p-Nitrophenyl-2-aminothiazol-5-ylsulphone. The TPSA of 155.0 Ų indicates high polarity, suggesting p-Nitrophenyl-2-aminothiazol-5-ylsulphone may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, p-Nitrophenyl-2-aminothiazol-5-ylsulphone has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of p-Nitrophenyl-2-aminothiazol-5-ylsulphone?
The CAS number of p-Nitrophenyl-2-aminothiazol-5-ylsulphone is 39565-05-4.
What is the molecular formula of p-Nitrophenyl-2-aminothiazol-5-ylsulphone?
The molecular formula of p-Nitrophenyl-2-aminothiazol-5-ylsulphone is C9H7N3O4S2.
What is the molecular weight of p-Nitrophenyl-2-aminothiazol-5-ylsulphone?
The molecular weight of p-Nitrophenyl-2-aminothiazol-5-ylsulphone is 284.9878 g/mol.
What are the applications of p-Nitrophenyl-2-aminothiazol-5-ylsulphone?
p-Nitrophenyl-2-aminothiazol-5-ylsulphone is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies...
Where can I buy p-Nitrophenyl-2-aminothiazol-5-ylsulphone?
You can request a quote for p-Nitrophenyl-2-aminothiazol-5-ylsulphone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for p-Nitrophenyl-2-aminothiazol-5-ylsulphone?
Yes, CoreyChem provides custom synthesis services for p-Nitrophenyl-2-aminothiazol-5-ylsulphone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.